Cisplatin

A member of the family of chemotherapy drugs known as platinum containing compounds or alkylating agents, Cisplatin has been in use for many years and was the first member in its class of drugs. In addition to treating mesothelioma, it has historically been used to treat testicular, bladder, ovarian, lung, and stomach cancers as well.

Technically speaking, cisplatin acts by cross-linking DNA in various different ways, making it impossible for rapidly dividing cells to duplicate their DNA for mitosis. When it was approved for use in 1978, it transformed the treatment of many different types of cancers. It is often used together with other chemo drugs.

Cisplatin’s side effects can be more severe than its more recent counterparts, as is usually the case with drugs that have been on the market for several decades. As new drugs are developed, scientists determine ways to lessen serious side effects.

Treatment

Cisplatin is administered intravenously or through a central line inserted for the purpose of prolonged chemotherapy.

Side Effects

Kidney failure (nephrotoxicity) – This is a major concern with cisplatin. Patients will be advised to drink lots of water and doctors will determine the patient’s renal function before suggesting the use of this drug.
Nerve damage
Nausea and vomiting – Your doctor will try to control this symptom with other forms of medication as these side effects can be quite severe with cisplatin.
Hair loss
Hearing loss
Increased chance of infection due to reduction in white blood cells
Inability to clot due to reduction in platelets
Fatigue

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Temple City Council to determine fate of asbestos-riddled former hotel A historic building located in Temple, Texas may soon fall. The building deemed as a gem to some and an ey ...

New Jersey firehouse to undergo asbestos abatement to allay mesothelioma worries d Senior Services has extended the deadline by 30 days. "We had asked for an extension beca ...

Mesothelioma victim wins settlement from former employer A man from Tyneside, England has won a payout from his former employers. 18 months ago, Mr. Wilfrid Craig ...

Temple City Council to determine fate of asbestos-riddled former hotel
A historic building located in Temple, Texas may soon fall. The building deemed as a gem to some and an ey ...

New Jersey firehouse to undergo asbestos abatement to allay mesothelioma worries d Senior Services has extended the deadline by 30 days.

"We had asked for an extension beca ...

Mesothelioma victim wins settlement from former employer
A man from Tyneside, England has won a payout from his former employers. 18 months ago, Mr. Wilfrid Craig ...